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. 2022 Dec 14;14(4):407–418. doi: 10.1111/1759-7714.14760

FIGURE 5.

FIGURE 5

Elevated L1CAM expression is associated with extracellular matrix (ECM) remodeling and RAS activation. The gene set positively correlated with L1CAM levels associated with (a) EMT and (b) RAS/MAPK pathway. The transcriptomes of LUSC patients with high L1CAM expression are associated with (c) collagen formation and (d) FGFR3 activation. (e) Pathway and (f) hub gene analysis of the transcriptomes of LUSC patients with high L1CAM expression. ***p < 0.005