Table 2.

Serum miRNAs expression in frail subjects and in robust subjects before and after intervention.

	Frail subjects before intervention	Frail subjects after intervention	Robust subjects before intervention	Robust subjects after intervention
miR-93-5p (copies/ng)	1.04 × 103; 1.33 × 102–5.83 × 103	2.67 × 102; 0.00–6.23 × 102	6.17 × 102; 3.25 × 101–6.79 × 103	3.25 × 102; 0.00–9.00 × 102*
miR-155-5p (copies/ng)	0.00; 0.00–1.39 × 102	6.41 × 101; 0.00–1.90 × 102	0.00; 0.00–1.56 × 102	4.48 × 101; 0.00–1.50 × 102^
miR-421-3p (copies/ng)	0.00; 0.00–3.03 × 102	0.00; 0.00–2.31 × 102	0.00; 0.00–2.15 × 102	0.00; 0.00–5.58 × 102
miR-425-5p (copies/ng)	5.25 × 104; 0.00–2.54 × 105	2.67 × 102; 0.00–6.68 × 102	6.33 × 102; 0.00–2.01 × 105	0.00; 0.00–4.50 × 102
miR-451a (copies/ng)	6.59 × 104; 1.12 × 104–2.54 × 105	6.56 × 103; 3.03 × 103–1.78 × 104	2.31 × 104; 1.94 × 103–2.01 × 105	1.20 × 104; 3.23 × 103-3.72 × 104
miR-495-3p (copies/ng)	4.39 × 102; 2.20 × 102–1.58 × 103	1.17 × 102; 0.00–4.65 × 102#	3.20 × 102; 1.83 × 102–1.25 × 103	3.07 × 102; 0.00–1.44 × 103*
miR-744-5p (copies/ng)	0.00; 0.00–1.08 × 102	0.00; 0.00–1.00 × 102	0.00; 0.00–1.56 × 102	0.00; 0.00–1.17 × 102

Data are reported as median and interquartile range.

*p = 0.02 Robust subjects before vs. after intervention.

#p = 0.001 Frail subjects before vs. after intervention.

^p = 0.05 Robust subjects before vs. after intervention.