TABLE 2.

Methylated DNA-binding proteins

Proteina	Molecular mass (kDa)	Binding sequencea	Reference(s)
DNA MTase	190, 175, 150	NDb	10
MeCP1	120	>15 mCpGs	106
MeCP2	84	A single mCpG site	90, 107
MDBP	250	5′-ATmCGTCAmCGGmCGAT-3′	63, 77
MDBP-2-H1	21 (monomer), 42 (dimer)	5′-TTCACCTTmCGCTATGAGGGGGATCATACTGG-3′	68, 127
Slp promoter binding protein	ND	(5′-TTCmCGGGC-3′)2	166
Xist promoter binding protein	100	5′-GmCGCmCGmCGG-3′c	64

^amC, 5-methylcytosine residue; MeCP, methyl-CpG binding protein; MDBP, methylated DNA-binding protein; H1, histone H1. 

^bND, not determined. 

^cXist promoter-binding protein preferentially binds to the DNA sequence when at least one of the three CpG sites is methylated.