Skip to main content
. 2022 Dec 13;14(1):464–478. doi: 10.1002/jcsm.13148

Figure 4.

Figure 4

AdipoRon drastically blunts diet‐ or age‐induced accumulation of intramyocellular lipids (IMCL) in middle‐aged obese mice. (A) IMCL content of soleus in peripheral and central subcellular regions in type 1 and 2a fibres stained by Bodipy and (B) IMCL content of EDL in subcellular regions in type 2x and 2b fibres. IMCL content in each region was expressed as the percentage of stained area normalized to total fibre area. Symbols for differences among central regions are in dark blue, among peripheral regions in turquoise blue, and those for the total content in black. (C) LD size in peripheral and central subcellular regions in type 1 and 2a fibres from soleus and (D) in type 2x and 2b fibres from EDL. Data are means ± SEM for five mice per group. Statistical analysis was performed using one‐way ANOVA followed by Tukey's test (comparing three groups of O‐mice) or by unpaired two‐tailed t‐test (Y‐ND vs. O‐ND). $ P < 0.05 versus Y‐ND mice. *P < 0.05, **P < 0.01 versus O‐ND mice. # P < 0.05, ## P < 0.01, ### P < 0.001 versus O‐HFD mice.