FIG. 3.
Homologies between the protein tyrosine phosphatase SptP of S. typhimurium, the cytotoxin YopE and the tyrosine phosphatase YopH from Yersinia spp., and the P. aeruginosa ExoS ADP-ribosyltransferase. Identically shaded boxes indicate regions of sequence similarities. The catalytic cysteine residue in the carboxy-terminal parts of SptP and YopH are shown. The predicted catalytic domain of ExoS is located in the carboxy-terminal quarter of the protein (stippled) (253).