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. 2022 Nov 8;66(3):472–481. doi: 10.1007/s00125-022-05821-3

Table 2.

Association of SAF with echocardiographic parameters and LV systolic and diastolic function

Outcome β (95%CI)
LVEF
 Model 1a −1.14 (−1.61, –0.67)
 Model 2b −0.98 (−1.45, −0.50)
E/e′
 Model 1a 0.24 (−0.05, 0.54)
 Model 2b 0.13 (−0.17, 0.43)
E/A
 Model 1a 0.01 (−0.01, 0.03)
 Model 2b 0.01 (−0.02, 0.03)
LA diameter
 Model 1a 0.26 (−0.19, 0.70)
 Model 2b 0.07 (−0.36, 0.50)
LVM index
 Model 1a −1.26 (−3.25, 0.72)
 Model 2b −1.24 (−3.24, 0.77)

Mean difference (β) (95% CI) for one unit increase in SAF was calculated using linear regression

aModel 1 adjusted for age and sex

bModel 2 adjusted for age, sex, CHD, type 2 diabetes, hypertension, smoking status, waist circumference, monthly income and physical activity

The number of individuals with available data on outcomes was 2328 for LVEF, 2295 for E/e′, 2307 for E/A, 2343 for LA diameter and 1181 for LVM index