Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 27;28(1):1. doi: 10.1007/s10911-023-09528-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Hyaluronan is heterogeneously deposited throughout mammary tumors. Immunofluorescence microscopy for hyaluronic acid binding protein (HABP; green) and DAPI nuclear stain alongside hematoxylin and eosin (H&E) - stained images identifying hyaluronan (HA) deposition within three murine models of breast cancer: (A) 4T1 and (B) HC11/R1-LM. H&E images of 4T1 and HC11/R1-LM tumors highlight the highly cellular tumor adjacent to the normal, adipocyte-rich mammary gland. Inserts identify intratumoral and peritumoral regions within each tumor. Whole tumor images were acquired on Leica DM6000B (IF) and DM5500B (H&E) microscopes at 200× and 100× magnification, respectively, and stitched together via the LAS V3.8 software. Inserts were acquired on Leica DM6000B (IF) and DM5500B (H&E) microscopes at 20× magnification. Scale bars represent 100 µM