Table 1.

Characteristics of the randomized controlled trails included in the study

Author	Country	Study design	Health status	Outcome	Sample size	Age(y)	BMI (kg/m3)	SBP/DBP (mmHg)	Duration (week)	Intervention	Control
Ambring et al. [28]	Sweden	Crossover	Healthy	FBF	22	43	26	-	12	MedDiet	Swedish diet
Buscemi et al. [29]	Italy	Parallel	Obese	FMD	20	38	34.2	128/88	8	MedDiet	Atkins low carbohydrate diet
Ceriello et al. [30]	Spain	Parallel	DM2	FMD	24	-	29.5	116/78	12	MedDiet + MUFA	Low-fat diet
Davis et al. [20]	Australia	Parallel	Healthy	FMD	166	71	26.9	124/71	24	MedDiet	Habitual diet
Esposito et al. [31]	Italy	Parallel	MetS	EFS	180	44	28	135/86	96	MedDiet	Prudent diet
Fuentes et al. [32]	Spain	Crossover	Hypercholestrolemic	FMD, BVS	22	40	-	-	8	MedDiet + MUFA	NCEP-1 diet
Jaacks et al. [33]	USA	Parallel	Overweight	FMD	30	51	31.5	-	8	MedDiet	Habitual diet
Klonizakis et al. [34]	UK	Parallel	Healthy	CM	22	55	30.5	127/79	8	MedDiet + exercise	Non-MedDiet + exercise
Maiorino et al. [35]	Italy	Parallel	DM2	CIMT	215	52	29.6	140/87	121	MedDiet	Low-fat diet
Marin et al. [36]	Spain	Crossover	Healthy	CM	20	67	31.9	-	4	MedDiet	SFA diet
Murie-Fernandez et al. [37]	Spain	Parallel	CVD risk	CIMT	187	67	29.4	-	48	G1:MedDiet + EVOO	Low-fat diet
										G2: MedDiet + nuts
Sala-Vila et al. [38]	Spain	Parallel	CVD risk	ICA-IMT	175	66	29.6	150/81	115	G1:MedDiet + EVOO	Low-fat diet
										G2: MedDiet + nuts
Thomazella et al. [39]	Brazil	Parallel	ACS	FMD, BVS	42	55	26.4	136/84	12	MedDiet	Low-fat diet
Torres-Peña et al. [40]	Spain	Parallel	DM2	FMD	438	61	31.8	-	72	MedDiet + EVOO	Low-fat diet
Torres-Peña et al. [40]	Spain	Parallel	pDM2	FMD	289	58	30.3	-	72	MedDiet + EVOO	Low-fat diet
Torres-Peña et al. [40]	Spain	Parallel	Healthy	FMD	78	56	29.5	-	72	MedDiet + EVOO	Low-fat diet
Yubero-Serrano et al. [41]	Spain	Parallel	CHD	FMD	805	60	30.9	137/77	52	MedDiet	Low-fat diet

ACS acute coronary syndromes, BVS baseline vessel size, CHD coronary heart disease, CIMT carotid intima-media thickness, CM cutaneous microvascular function, CVD risk risk of cardiovascular disease, DBP diastolic blood pressure, DM2 type 2 diabetes, EFS endothelial function score, EVOO extra virgin olive oil, FBF forearm blood flow, FMD flow-mediated dilation, G1 group 1, G2 group 2, ICA-IMT internal carotid intima-media thickness, MedDiet Mediterranean dietary pattern, MetS metabolic syndrome, n number of subjects, NCEP-1 The National Cholesterol Education Program Diet, pDM2 prediabetes, SBP systolic blood pressure