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. 2023 Jan 17;43(2):247–270. doi: 10.1007/s10875-022-01418-y

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© The Author(s) 2023, corrected publication 2024

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Fig. 2 — Depiction of how CD45RA may be re-expressed (highlighted in figure) despite not representing a truly naïve T lymphocyte. Unlike TEMRA cells, true naïve recent thymic emigrant T cells express CD31 and CCR7 surface markers. Gated from CD45⁺CD3⁺ T cells expressing either CD4 or CD8. CCR7, chemokine receptor 7; PD1, programmed death 1; LKRG1, killer lectin inhibitory receptor 1; TCM, T central memory; TEMRA, T effector memory re-expressing CD45RA; TEM, T effector memory. Figure created using BioRender.com