Table 3.

Multivariate logistic regression assessing for association of various laboratory values and active disease, defined by BASDAI ≥ 4

Laboratory variables (cut-off values)	Number of observations	Odds ratio (95% CI)	p-value	AIC	BIC
NLR (3.669)	1026	6.931 (2.094–22.946)	0.002	1180.231	1219.699
PLR (242.466)	Did not perform multivariate logistic regression, univariate regression showed no statistical significance
ESR (22.000 mm/Hr)	858	1.333 (0.903–1.966)	0.148	not performed	not performed
CRP (1.980 mg/dL)	758	2.745 (1.479–5.096)	0.001	869.018	906.063
NLR (+ CRP)	635	12.182 (1.611–92.109)	0.015	703.121	743.204

Controlled for age, duration of disease, duration on TNFi, pack years smoking, working status.

The final model (+ CRP) tested for associations of NLR and BASDAI > 4 after included CRP in the model.

BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; CI, confidence interval; AIC, Akaike Information Criteria; BIC, Bayesian Information Criteria; mm/Hr, millimeters per hour; mg/dL, milligrams per deciliter