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. 2023 Jan 19;10:1087957. doi: 10.3389/fmed.2023.1087957

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Copyright © 2023 Ghidaglia, Laurent, Sebagh, Pascale, Durand, Golse and Besson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Case-mix of hepatocellular carcinoma (HCC) with various dual-tracer positron emission tomography (PET) profiles. The PET part of the non-contrast-enhanced PET/computed tomography (CT) data 18F fluorodeoxyglucose (18F-FDG on the left panel and 18F-choline on the right panel) of three HCCs (A–C) were retrospectively fused to their available contrast-enhanced MRI data (axial T1-weighted MRI pulse sequences with arterial phase contrast enhancement). (A) Dual-PET radiotracers negative uptake (HCC Grade III, with mVI). (B) Dual-PET radiotracers positive uptake (HCC Grade I, with mVI). (C) Negative 18F-FDG uptake but positive 18F-choline uptake (HCC Grade I-II, without mVI).