Skip to main content
. 2023 Jan 19;14:1016967. doi: 10.3389/fphar.2023.1016967

FIGURE 8.

FIGURE 8

GJF inhibited HepG2 cells growth in vitro. (A) The effect of GJF on the survival rate of HepG2 cells. (B) Effect of GJF on the cell mobility of HepG2 cells. (C) GJF induces hepatocellular arrest of HepG2 cells cycles. (D) GJF induces apoptosis in HepG2 cells. (E) Changes in the mRNA expression levels of related molecules in the PI3K/Akt pathway in HepG2 cell lines. Gene expression was evaluated by RT-qPCR, using the 2 −∆∆CT method. (CON, negative control treatment; GJF-L, treated with low concentrations (0.5 mg/ml) of GJF; GJF-M, treated with medium concentrations (1.0 mg/ml) of GJF; GJF-H, treated with medium concentrations (1.5 mg/ml) of GJF. Data are presented as the mean ± SD, and analysis of variance was used to determine the significance. *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group).