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Airway epithelial cell-specific deletion of HMGB1 compromises bacterial clearance of Tg+ mice. CFUs were counted in BALF from mice with different genotypes (Cre-/WT [blue open bar], Cre+/WT [red open bar], Cre-/Tg+ [solid blue bar], and Cre+/Tg+ [solid red bar] mice). The CFU values were log10-transformed. Error bars represent Mean ± SEM. One-way ANOVA followed by Tukey’s post hoc test was used for the statistical analysis. **p < 0.01, ****p < 0.0001.
