Table 3.
Outcomes.
| Early HFNC + CPAP | Delayed HFNC + CPAP | p-Value | |
|---|---|---|---|
| Endotracheal intubation, n (%) | 125 (34.5%) | 148 (41.8%) | 0.045 |
| 30-day mortality, n (%) | 31 (8.2%) | 59 (15.5%) | 0.002 |
| CPAP tolerance, n (%) | 310 (84.0%) | 265 (71.4%) | <0.0001 |
| Pneumothorax, n (%) | 7 (1.8%) | 10 (2.6%) | 0.46 |
| Pneumomediastinum, n (%) | 20 (5.3%) | 25 (6.6%) | 0.44 |
| IRCU admission days, median (IQR) | 6.0 (4.0–9.0) | 8.0 (5.0–11.0) | <0.0001 |
| Hospital admission days, median (IQR) | 18.0 (13.0–29.0) | 22.0 (15.0–36.0) | <0.0001 |
| NIRS duration, median (IQR) | 5.0 (3.0–7.0) | 6.0 (4.0–9.0) | <0.0001 |
HFNC: high-flow nasal cannula, CPAP: continuous positive airway pressure, IRCU: intermediate respiratory care unit, IQR: interquartile range.