Table 4.
Multivariate analysis.
| OR | CI 95% | p-Value | ||
|---|---|---|---|---|
| Endotracheal intubation | ||||
| Age | 1.02 | 0.99 | 1.05 | 0.09 |
| Charlson Comorbidity Index | 1.21 | 0.99 | 1.48 | 0.054 |
| Delayed HFNC + CPAP | 1.93 | 1.27 | 2.91 | 0.002 |
| CPAP initial pressure | 1.16 | 0.97 | 1.39 | 0.08 |
| NIRS duration | 0.75 | 0.70 | 0.80 | <0.0001 |
| Time of symptom onset until IRCU admission | 0.86 | 0.80 | 0.92 | <0.0001 |
| 30-Day mortality | ||||
| Age | 1.055 | 1.01 | 1.09 | 0.003 |
| Charlson Comorbidity Index | 1.29 | 1.08 | 1.55 | 0.005 |
| Delayed HFNC + CPAP | 2.11 | 1.17 | 3.82 | 0.01 |
| CPAP initial pressure | 1.3 | 1.01 | 1.66 | 0.036 |
| Days of respiratory support | 0.93 | 0.88 | 0.98 | 0.009 |
HFNC: high-flow nasal cannula, CPAP: continuous positive airway pressure, IRCU: intermediate respiratory care unit, OR: odds ratio, CI: confidence interval.