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Common findings in spleen (A) and lymph node (B): Spleens show diminished white pulp and increased red-to-white pulp ratio, with areas of hemorrhage (A). On low magnification, lymph nodes show attenuation of follicular architecture (B, left) and varying degrees of sinus histiocytosis (B, middle), with some cases also showing prominent hemophagocytosis (B, right, highlighted by CD163).
