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. 2023 Feb 2;16(2):197–211. doi: 10.1016/j.path.2023.01.007

Fig. 7.

Fig. 7

Histologic and cytologic findings of COVID-19 vaccine-related lymphadenopathy: An individual in their twenties suddenly developed axillary, cervical, and supraclavicular lymphadenopathy (up to 2 cm in greatest dimension) 1 week after receiving the second mRNA COVID-19 vaccine in the deltoid muscle. H&E sections (A, B) and IHC for CD3 (C), CD20 (D), CD10 (E), and Bcl-2 (F) of lymph nodes (ipsilateral to vaccine site) show marked reactive lymphoid hyperplasia. Aspirate smears (G, H) show a polymorphous mixture of small and large lymphocytes, occasional admixed inflammatory cells, tingible-body macrophages, and lymphoglandular bodies (cytoplasmic fragments). Case and images kindly provided by Dr Amy Duffield.