Table 3.
Admission to ICU |
Mechanical ventilation |
Death |
Adverse outcome |
Duration of hospitalization |
||||||
---|---|---|---|---|---|---|---|---|---|---|
ARR (95 % CI) | p-value | ARR (95 % CI) | p-value | ARR (95 % CI) | p-value | ARR (95 % CI) | p-value | ΙRR (95 % CI) | p-value | |
COVID-19 vaccination | ||||||||||
no vaccination | ref. | ref. | ref. | ref. | ref. | |||||
partial vaccination | 0.46 (0.22–0.96) | 0.037 | 0.47 (0.22–1.04) | 0.062 | 0.72 (0.50–1.02) | 0.066 | 0.62 (0.45–0.87) | 0.006 | 0.86 (0.75–0.99) | 0.03 |
full (booster) vaccination | 0.49 (0.29–0.84) | 0.009 | 0.43 (0.23–0.80) | 0.007 | 0.57 (0.42–0.78) | <0.001 | 0.54 (0.41–0.72) | <0.001 | 0.79 (0.70–0.89) | <0.001 |
Diagnosis to admission* | 1.16 (1.09–1.24) | <0.001 | 1.10 (1.03–1.16) | 0.002 | 1.03 (0.99–1.07) | 0.095 | 1.05 (1.02–1.09) | 0.002 | 1.03 (1.01–1.04) | <0.001 |
Age | 1.02 (1.00–1.03) | 0.014 | 1.01 (1.00–1.03) | 0.038 | 1.06 (1.05–1.07) | <0.001 | 1.05 (1.04–1.06) | <0.001 | 1.01 (1.00–1.01) | <0.001 |
Sex | ||||||||||
male | ref. | ref.. | ref. | ref. | ref. | |||||
female | 0.88 (0.56–1.37) | 0.564 | 0.81 (0.55–1.50) | 0.708 | 0.94 (0.72–1.22) | 0.63 | 0.88 (0.69–1.11) | 0.276 | 0.89 (0.80–0.99) | 0.027 |
Comorbidities | ||||||||||
none | ref. | ref. | ref. | ref. | ref. | |||||
one | 1.02 (0.56–1.85) | 0.952 | 0.94 (0.50–1.76) | 0.856 | 1.37 (0.89–2.12) | 0.148 | 1.22 (0.84–1.76) | 0.29 | 1.01 (0.89–1.15) | 0.906 |
two | 0.90 (0.48–1.69) | 0.735 | 1.01 (0.53–1.93) | 0.98 | 1.48 (0.94–2.33) | 0.092 | 1.29 (0.87–1.90) | 0.201 | 1.16 (1.00–1.36) | 0.052 |
three or more | 1.84 (0.82–3.67) | 0.086 | 1.17 (0.48–2.86) | 0.728 | 2.47 (1.55–3.93) | <0.001 | 2.10 (1.41–3.13) | <0.001 | 1.17 (0.98–1.39) | 0.077 |
All regression models included hospital fixed-effects.
COVID-19: coronavirus disease 2019; ICU: intensive care unit; ARR: adjusted relative risk; IRR: incidence rate ratio; CI: CI: confidence interval; Ref: reference.
time elapsed from diagnosis to admission (days).