TABLE 1.

Patients' characteristics at baseline

	Total	TR	IER	IRR	NR
	n = 404	n = 84 (20.8)	n = 94 (23.3)	n = 55 (13.6)	n = 171 (42.3)
Age (years)	34.0 (24.0–45.0)	35.0 (25.5–45.0)	33.5 (24.0–43.0)	33.0 (23.0–53.0)	33.0 (23.0–44.0)
Disease duration (years)	4.0 (1.0–11.0)	6 (2.0–14.0)	4.0 (1.0–9.0)	3.0 (1.0–10.0)	4.0 (1.0–10.0)
Time between exams (months)	2.0 (0.0–4.0)	2 (1.0–4.0)	3 (0–4.0)	1 (1.0–3.0)	1 (0–3.0)
Female gender (%)	213 (52.7)	52 (61.9) a	52 (55.3)	30 (54.5)	79 (46.2) a
Disease location
Ileal (L1)	246 (60.9)	50 (59.5)	53 (56.4)	32 (58.2)	111 (64.9)
Ileo‐colonic (L3)	158 (39.1)	34 (40.5)	41 (43.6)	23 (41.8)	60 (35.1)
Disease behavior
Inflammatory (B1)	158 (39.1)	41 (48.8) b	39 (41.5)	25 (45.5) c	53 (31.0) b , c
Stricturing (B2)	134 (33.2)	27 (32.1) b	31 (33.0)	16 (29.1) c	60 (35.1) b , c
Penetrating (B3)	112 (27.7)	16 (19.0) b	24 (25.5)	14 (25.5) c	58 (33.9) b , c
Perianal disease (%)	81 (20.0)	19 (22.6)	17 (18.1)	9 (16.4)	36 (21.1)
Upper GI disease (%)	74 (18.3)	15 (17.9)	19 (20.2)	9 (16.4)	31 (18.1)
Previous surgery (%)	121 (30.0)	34 (40.5) d , e	25 (26.6) d , f	24 (43.6) e , f	38 (22.2) e
IM at baseline (%)	197 (48.8)	45 (53.6)	47 (50.0)	29 (52.7)	76 (44.4)
Biologic at baseline (%)	86 (21.3)	26 (31.0) b	19 (20.2)	14 (25.5)	27 (15.8) b
Biologic exposure (%)
None	302 (74.8)	56 (66.7) b	68 (72.3)	40 (72.7)	138 (80.7) b
1 biologic	80 (19.8)	24 (28.6) b	19 (20.2)	12 (21.8)	25 (14.6) b
2 biologics	22 (5.4)	4 (4.8) b	7 (7.4)	3 (5.5)	8 (4.7) b

Note: Continuous variables are expressed as median (interquartile range). Comparisons with a p value < 0.1 are presented.

Abbreviations: GI, gastrointestinal; IER, isolated endoscopic remission; IM, immunomodulator; IRR, isolated radiologic remission; NR, no remission; TR, transmural remission. Significant comparisons are highlighted in bold.

^a p = 0.02.

^b p = 0.008.

^c p = 0.072.

^d p = 0.057.

^e p = 0.003.

^f p = 0.046.