Table 2.
Association between LXA4 and the incidence of T2DM.
| N (case) | Model 1 | P value | Model 2 | P value | Model 3 | P value | |
|---|---|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
| LXA4 quartiles | |||||||
| Q 1 | 689 (52) | Ref | 1.0 | Ref | 1.0 | Ref | 1.0 |
| Q 2 | 676 (41) | 0.79 (0.52-1.19) | 0.256 | 0.84 (0.55-1.26) | 0.389 | 0.90 (0.60-1.36) | 0.620 |
| Q 3 | 685 (46) | 0.88 (0.59-1.31) | 0.529 | 0.92 (0.62-1.37) | 0.671 | 0.90 (0.60-1.35) | 0.615 |
| Q 4 | 705 (33) | 0.61 (0.39-0.94) | 0.026 | 0.64 (0.41-0.99) | 0.046 | 0.62 (0.40-0.96) | 0.031 |
| P trend | 0.052 | 0.051 | 0.081 | 0.045 | |||
| LXA4 > 2.84 ng/mL | 942 (44) | 0.66 (0.47-0.92) | 0.016 | 0.68 (0.48-0.95) | 0.025 | 0.63 (0.45-0.89) | 0.009 |
| Per 1-SD increase | 0.77 (0.51-1.16) | 0.215 | 0.79 (0.53-1.17) | 0.240 | 0.78 (0.51-1.18) | 0.239 | |
Model 1: unadjusted.
Model 2: adjusted for baseline age, gender, BMI, smoking, alcohol consumption.
Model 3: adjusted for baseline age, gender, BMI, smoking, alcohol consumption, hypertension, dyslipidemia, hs-CRP, family history of diabetes and physical activity.
Significant data in the table are in bold.