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. 2023 Feb 2;9:40. doi: 10.1038/s41420-023-01315-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A qRT-PCR analyses of CDC7 expression in H69-AR(left) and H446-DDP(right) 48 h after transfected with CDC7 siRNA. B Western blot analyses of CDC7 and MCM2 in H69-AR(left) and H446-DDP(right) 48 h after transfected with CDC7 siRNA. IC₅₀ and the statistics of IC₅₀ of DDP in H69-AR (C, D) and H446-DDP (E, F) transfected with scramble or si-CDC7. Cell viability of H69-AR (G) and H446-DDP (H) transfected with si-CDC7 using CCK-8 assay. All data are representative of three independent experiments (mean ± SEM).