Skip to main content
. 2023 Feb 2;9:40. doi: 10.1038/s41420-023-01315-2

Fig. 4. XL413 increases apoptosis induced by chemo-treatment in resistant SCLC cells.

Fig. 4

A Western blot analyses of apoptotic related proteins in H69-AR treated with negative control, XL413(50 μM), DDP and VP16(1 μg/ml, 100 μg/ml) and combined treatment for 48 h. B Western blot analyses of apoptotic related proteins in H446-DDP treated with negative control, XL413(80 μM), DDP, and VP16(5 μg/ml, 80 μg/ml) and combined treatment for 48 h. C Apoptotic flow cytometry of H69-AR with indicated treatment for 48 h. D Apoptotic flow cytometry of H446-DDP with indicated treatment for 48 h. Apoptotic cells statistical analyses of H69-AR (E) and H446-DDP (F).