Figure 1.

Sedimentation profiles of 40 μM Aβ42 after different incubation times (1, 10, 19, 25, 35, and 48 h) at 20°C in triplicates from top to bottom. The raw data (colored dots) are shown together with fitted Lamm equation solutions (black lines) from the c(s) model implemented in Sedfit. For clarity, only every sixth scan is shown. Below each graph are the residuals depicted, i.e., the deviation of the fit from the measured data. Different colors indicate different time points of detection during sedimentation as shown in the legend on top. The detection wavelengths vary between different measurements. To see this figure in color, go online.