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. 2023 Feb 1;19(2):225–242. doi: 10.5664/jcsm.10298

Table 4.

Studies assessing respiratory event–related metrics.

Study Study Size/Type Type of PSG (Level 1 or 2) Sex (% male) Mean BMI (kg/m2) Mean AHI (/h) Mean Age (years) % OSA Participants Metric Outcome Results
Goh (2018)53 Singapore 821/Retro 1 67 28 28 48 100 Apneic and Hypopneic load ESS Linear regression analysis found age (P < .001), apnea load (P = .005), REM (P = .021) and stage 1 sleep duration (P = .042) were independent factors correlated to ESS.
Butler (2019)44 USA 5712/Retro of Pros 1 48 28.1 13.8 63.3 67 Respiratory event duration All-cause mortality Individuals with the shortest-duration events had a significantly increased hazard ratio for all-cause mortality
Kim (2021)31 USA 2055/Cross-sectional 1 46 28.7 14.8 68.4 Not referenced Duty cycle and IFL Hypertension Higher duty cycle and IFL were associated with lower BP
Mediano (2007)54 Spain 40/Retro 1 100 32 61 50 100 Apnea duration EDS Longer apnea duration can be a determinant of excessive daytime sleepiness in OSA patients

AHI = apnea hypopnea index, BMI = body mass index, BP = blood pressure, EDS = excessive daytime sleepiness, ESS = Epworth Sleepiness Scale, IFL = inspiratory flow limitation, ODI = oxygen desaturation index, OSA = obstructive sleep apnea, Pros = prospective, PSG = polysomnography, RDI = respiratory disturbance index, REM = rapid eye movement, Retro = Retrospective, Retro of Pros = retrospective analysis of prospective study, SD = standard deviation.