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. 2022 Nov 6;17(2):195–229. doi: 10.1002/1878-0261.13326

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© 2022 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Functions of m⁶A modification on mRNA. A schematic image of the roles of m⁶A on mRNA. m⁶A modification on mRNA plays different roles in nucleus and cytoplasm. (A) Regulation of transcription, (B) regulation of splicing, (C) alteration of RNA structure, (D) facilitation of mRNA export, (E) determination of APA, (F) regulation of translation and (G) regulation of mRNA stability.