TABLE 3.
Patients with melanoma of the lower leg and foot with analyzed in-transit metastases patterns.
| n | Conventional photography n = 24 |
3D-photography n = 22 |
||
| Gender | Male | 10 | 5 (21%) | 5 (23%) |
| Female | 36 | 19 (79%) | 17 (77%) | |
| Male-to-female ratio | 1:3.8 | 1:3.4 | ||
| Age (years) | Median | 66 | 60 | |
| Mean | 70 | 66 | ||
| Range | 28–87 | 29–87 | ||
| Histologic subtype | SSM | 12 | 7 (29%) | 5 (23%) |
| NM | 9 | 6 (25%) | 3 (14%) | |
| ALM | 11 | 5 (21%) | 6 (27%) | |
| NOS | 14 | 6 (25%) | 8 (36%) | |
| Tumor thickness (mm)* | Median | 3.5 | 3.3 | |
| Mean | 3.6 | 3.0 | ||
| Range | 0.2–7.3 | 0.3–7.3 | ||
| Unknown | 1 (4%) | 2 (9%) | ||
| Ulceration* | Present | 21 | 15 (79%) | 6 (30%) |
| Absent | 18 | 4 (21%) | 14 (70%) | |
| Location of melanoma | Foot | 15 | 8 (33%) | 7 (32%) |
| Lower leg | 31 | 16 (67%) | 15 (68%) | |
| Number of ITM | 1–5 | 13 | 4 (17%) | 8 (36%) |
| 6–10 | 12 | 6 (25%) | 7 (32%) | |
| 11–20 | 11 | 7 (29%) | 4 (18%) | |
| >20 | 10 | 7 (29%) | 3 (14%) | |
| Time between melanoma and first ITM (months) | Median | 8 | 31 | |
| Mean | 22 | 53 | ||
| Range | 0–120 | 0–244 |
ITM, in-transit metastasis; SSM, superficial spreading melanoma; NM, nodular melanoma; ALM, acral lentiginous melanoma; LMM, lentigo maligna melanoma; NOS, not otherwise specified; 3D, three-dimensional.
*Ulceration status was unknown (n = 7). Patient characteristics of 46 patients with primary melanoma of the lower extremity and the foot with in-transit metastases were analyzed by conventional or 3D photography.