Table 3.

Data Collected at Each Visit.

Timepoint	Baseline-1 cycle	Treatment phase			Follow-up phase
	~D0	Cycle 1	Cycle 2	Cycle n	Every 3 mo
		D1 ± 3	D21 ± 3
Eligibility screening	×
Informed consent	×
Medical history	×
Clinical observation	×	×	×	×	×
MDASI–LC	×	Once a week
Imaging examination	×	Every two treatment cycles			×
Tumor marker assessment (optional)	×	×	×	×
Safety observation	×	×	×	×	×
NCI AEs		×	×	×	×
Peripheral blood examination	×			×
Survival status					×

Abbreviations: MDASI-LC, M.D. Anderson Symptom Inventory-Lung Cancer; NCI, National Cancer Institute; AEs, adverse events.