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. 2023 Jan 31;30:10732748231154711. doi: 10.1177/10732748231154711

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Proportion of patients presenting for potential curative treatment. Legend: Any given patient may be deemed inoperable at time of diagnosis or irresectable through clinical (image-based) staging. Definitions for borderline/locally advanced cancers are floating, with variation in management. More effective systemic therapy (eg FOLFIRINOX) is increasingly introduced in the pre-operative setting, with more resections offered after therapy, possibly influencing the pathological TNM-staging and interpretation of its prognostic role. Better predictive and prognostic biomarkers of cancer biology are needed. Reproduced with permission from Roalsø et al. Copyright © 2020 The Author(s). Published by Elsevier Ltd. All rights reserved.