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. 2023 Jan 19;12:1048127. doi: 10.3389/fonc.2022.1048127

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Copyright © 2023 Guo, Lu and Xiong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The ENSR00000148786 putative target TMEM43/LUMA potentially induced irAE from B cells. (A, B) Significant correlation between irAE and expression levels of eRNA ENSR00000148786 (A) or TMEM43/LUMA (B, C) Sorted mean expression levels of eRNA ENSR00000148786 across cancer types, with the arrow indicating the highest expression in DLBC (diffuse large B-cell lymphoma). (D) Significant eRNA-target correlation between ENSR00000148786 and TMEM43/LUMA was the highest in DLBC among the three significant cancer types.