Table 1.
Baseline Characteristics of Patients with Definite Diagnosis and Staining Index with Fibroblast Activation Protein
| Diagnostic Criteria | IPF (n = 7) | Non-IPF (n = 26) |
||
|---|---|---|---|---|
| Idiopathic NSIP (n = 7) | ASS (n = 13) | RA (n = 6) | ||
| Male sex, n (%) | 5 (71.4) | 3 (37.5) | 4 (30.8) | 3 (50) |
| Age (yr), mean (range) | 62.1 (57–70) | 47.9 (40–60) | 52.8 (34–68) | 53.3 (34–61) |
| Autoantibody, n (%) | ||||
| ANA | 0 | 0 | 10 (76.9) | 3 (50) |
| Anti-Ro-52 | 0 | 0 | 12 (92.3) | 2 (33.3) |
| Anti-Jo-1 | 0 | 0 | 4 (30.8) | 0 |
| Anti-PL-12 | 0 | 0 | 4 (30.8) | 0 |
| Anti-CCP | 0 | 0 | 0 | 4 (66.7) |
| RF (U/ml), mean (range) | <20 | <20 | <20 | 365.8 (22–717) |
| HRCT type, n (%) | ||||
| NSIP | 0 | 7 (100) | 9 (69.2) | 1 (16.7) |
| UIP | 7 (100) | 0 | 4 (30.8) | 5 (83.3) |
| Fibroblast foci, n (%) | ||||
| None | 0 | 4 (57.1) | 4 (30.8) | — |
| Few/little | 1 (14.3) | 3 (42.9) | 4 (30.8) | 1 (16.7) |
| Visible/existent | 5 (71.4) | 0 | 4 (30.8) | 5 (83.3) |
| Great amount/broad | 1 (14.3) | 0 | 1 (7.7) | — |
| FAP+ (%), mean (range) | 8.6 (3.0–23.1) | 4.1 (0.1–15.1) | 6.2 (0.1–12.2) | 8.3 (3.8–13.1) |
Definition of abbreviations: ANA = antinuclear antibody; ASS = antisynthetase syndrome; CCP = cyclic citrullinated peptide; HRCT = high-resolution computed tomography; IPF = idiopathic pulmonary fibrosis; NSIP = nonspecific interstitial pneumonitis; RA = rheumatoid arthritis; RF = rheumatoid factor; UIP = usually interstitial pneumonia.