Table 5.

Trough (Before Dose) Plasma GB0139 Concentrations (ng/ml) in Patients with COVID-19

	Baseline	Day 3	Day 5	Day 8	Day 11
N	18	20	12	9	4
Arithmetic mean (SD)	BLQ	22.91 (12.03)	8.58 (4.60)	6.66 (3.80)	5.85 (2.30)
CV, %	—	53	54	57	39
Geometric mean	—	19.94	7.81	6.01	5.50
Median (min–max)	BLQ	18.28	7.32	5.27	5.70
	(BLQ–BLQ)	(7.45–51.21)	(3.94–21.62)	(3.87–15.99)	(3.22–8.81)

Definition of abbreviations: BLQ = below the limit of quantitation (0.5 ng/ml); CV = coefficient of variation; SD = standard deviation.