Table 1.
The Nanoplatforms Loaded With Anticancer Drugs for Various Therapeutic/Imaging Agents, Targeting Drug Delivery, Stimuli Responses for Cancer Detection, and Treatment.
| Sl. no. | Nanoplatforms | Drug Encapsulated | Therapeutic/Imaging Agent | Targeting Drug Delivery | Stimuli Response | Applications | Ref. |
|---|---|---|---|---|---|---|---|
| 1. | Nanoporphyrins | DOX | Gd-CNPs | Passive | Illumination | MRI imaging/PET and photothermal therapy | 20 |
| 2. | Magnetic nanoparticle | Temozolomide | SPION | Passive | pH | MRI imaging | 21 |
| 3. | Metal Chelating Polymer (MCP) | Panitumumab | 111In and 177Lu | Passive and active | Radioactivity | PET imaging | 22 |
| 4. | PEI-PEG co-grafted polymer | 5-FU | siRNA | Passive | Enzyme | SPECT imaging | 23 |
| 5. | BiotinPVA | PTP1 | Rhodol green | Passive | Glutathione | Fluorescence imaging | 24 |
| 6. | HBPE-S polymeric nanoparticles | Taxol | – | Passive | pH | X-ray imaging | 25 |
| 7. | Magnetic nanoparticles (Dox@SMNPs) | DOX | 64Cu2+ | Passive | Heat | Micro PET imaging | 26 |
| 8. | DHP nanoparticle | Paclitaxel | Cynin fluorophore | Passive | Intracellular GSH | Fluorescent and Photoacoustic imaging | 27 |
| 9. | Nanoemulsions | Platinum | FA | Active | pH | MRI imaging | 28 |
| 10. | Albumin-coated Tobacco Mosaic Virus (TMV) | DOX | Cy5 and Gd(DOTA) | Active | pH | MRI imaging | 29 |
| 11. | Cyt C-HBPH nanoparticles | Cytochrome C | ICG | Passive | pH | Fluorescence imaging | 30 |
| 12. | PEI-oxliPt(IV) @RNBC/GOD (redox responsive nanocomplex | Oxaliplatin | RNase A protein and glucose oxidase | Passive | Enzyme | Confocal laser microscopy | 31 |
| 13. | FA-INPs | Folate | ICG | Active | Photothermal irradiation | NIR fluorescence imaging | 32 |
| 14. | Radiolabelled mesoporous silica nanoparticle | TRC105 antibody | DOX | Active | pH | PET imaging | 33 |
| 15. | DOX-SPIONS with nanomicellar | DOX | Chitosan | Passive | pH | Confocal Laser Scanning Microscope | 34 |