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. 2023 Jan 19;12:1097816. doi: 10.3389/fonc.2022.1097816

Table 2.

Correlation between the FR+-CTC count and clinical characteristics.

Characteristics CTC expression level χ2 p Characteristics CTC expression level χ2 p
Low (n=38) High(n=30) Low (n=38) High(n=30)
Age(years) 1.36 0.243 Clinical stage 3.51 0.061
<58 18(47.4%) 10(33.3%) I 20(52.6%) 9(30.0%)
≥58 20(52.6%) 20(66.7%) II+III+IV 18(47.4%) 21(70.0%)
Sex 0.5 0.481 PLT (×109/L) 1.56 0.211
Male 21(55.2%) 14(46.6%) <251 21(55.3%) 12(40.0%)
Female 17(44.8%) 16(53.4%) ≥251 17(44.7%) 18(60.0%)
Tumor size(cm) 0.68 0.411 NE(×109/L) 0.002 0.965
<2.79 19(50.0%) 18(60.0%) <5.34 23(60.5%) 18(60.0%)
≥2.79 19(50.0%) 12(40.0%) ≥5.34 15(39.5%) 12(40.0%)
Pathologic type 3.76 0.053 NLR 0.14 0.712
NSCLC 37(97.4%) 24(80.0%) <4.01 25(65.8%) 21(70.0%)
SCLC 1(2.6%) 6(20.0%) ≥4.01 13(34.2%) 9(30.0%)
Treatment 5.46 0.019 PLR 1.09 0.297
Surgery 13(34.2%) 3(10.0%) <183.1 25(65.8%) 16(53.3%)
Systemic therapy 25(65.8%) 27(90.0%) ≥183.1 13(34.2%) 14(46.7%)
T classification 7.84 0.005 dNLR 1.19 0.276
T1+T2 33(86.8%) 17(56.7%) <2.2 24(63.2%) 15(50.0%)
T3+T4 5(13.2%) 13(43.3%) ≥2.2 14(36.8%) 15(50.0%)
N classification 1.73 0.189 LC(×109/L) 0.19 0.666
N0 25(65.8%) 15(50.0%) <1.5 17(44.7%) 15(50.0%)
N1+N2+N3 13(34.2%) 15(50.0%) ≥1.5 21(55.3%) 15(50.0%)
Metastasis tatus 0.66 0.416
Yes 31(81.6%) 22(73.3%)
No 7(18.4%) 8(26.7%)

Values in bold mean p<0.05.