Table 2a:
Multivariable mixed effects model of characteristics associated with adverse events
| Adverse Event | ||||
|---|---|---|---|---|
|
|
||||
| Characteristic | Univariate OR | p-value | Multivariable OR | p-value |
| Age ≥ 60 vs. < 60 years | 3.23 (2.70–3.87) | <0.001 | 2.20 (1.80–2.70) | <0.001 |
| Female | 0.66 (0.57–0.79) | <0.001 | 0.92 (0.75–1.11) | 0.37 |
| Race | ||||
| White | Reference | Reference | - | - |
| Black | 1.19 (0.91–1.55) | 0.21 | - | - |
| Hispanic | 1.12 (0.81–1.54) | 0.51 | - | - |
| Other Race | 0.68 (0.46–1.03) | 0.66 | - | - |
| Structural Heart Disease | ||||
| None | Reference | Reference | Reference | Reference |
| CHD | 1.34 (0.73–2.47) | 0.35 | 1.60 (0.81–3.16) | 0.18 |
| HF, no CAD | 2.38 (1.96–2.90) | <0.001 | 1.59 (1.25–2.02) | <0.001 |
| HF, CAD | 3.56 (2.99–4.25) | <0.001 | 1.84 (1.48–2.30) | <0.001 |
| Comorbidities | ||||
| DM | 1.83 (1.54–2.18) | <0.001 | 0.91 (0.77–1.21) | 0.79 |
| Anemia | 7.63 (6.23–9.33) | <0.001 | 4.84 (3.79–6.19) | <0.001 |
| Atrial fibrillation | 2.17 (1.83–2.57) | <0.001 | 1.31 (1.06–1.61) | 0.01 |
| Admission characteristics | ||||
| Admit from home | Reference | Reference | Reference | Reference |
| Hospital transfer | 2.13 (1.77–2.56) | <0.001 | 1.58 (1.26–1.98) | <0.001 |
| Admit from ED | 2.15 (1.79–2.57) | <0.001 | 1.69 (1.38–2.08) | <0.001 |
| Year | 1.07 (1.05–1.09) | <0.001 | 1.02 (0.99–1.04) | 0.16 |
HF = Heart Failure; ED = Emergency Department; DM = Diabetes Mellitus; CAD = Coronary Artery Disease; CHD = Congenital Heart Disease