Table 1.

Study Population Characteristics

Study	Deficient	Normal	p value
Age (years)	42 + 2	40 + 4	0.17
FEV1 (% predicted)	101 + 3	107 + 4	0.058
FVC (% predicted)	103 + 6	104 + 4	0.43
TLC (% predicted)	105 + 4	104 + 4	0.82
DLcoa (% predicted)	112 + 4	103 + 5	0.22
$\mathrm{\Delta }$FEV1 (ml/year)	− 174 + 59	NA	NA
$\alpha$1-AT Level ($\mathrm{\mu }$M)	5.2 + 0.2	27.7 + 1.0	< 0.0001b

Values are expressed as mean and standard error of the mean (SE)

FEV₁, forced expiratory volume in one second; FVC, forced vital capacity; TLC,  total lung capacity; DL_CO, diffusing capacity; $\mathrm{\Delta }$ FEV₁, rate of decline FEV₁/year

^aSingle breath (uncorrected)

^bSignificant correlation