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. 2023 Feb 1;21:66. doi: 10.1186/s12967-023-03928-8

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — MitoDEGs in DCM; PPI network analysis and hub MitoDEGs identification. a, b Venn diagrams showed the number of upregulated a and downregulated b DEGs that overlap between GSE4745, GSE5606, GSE6880, MitoCarta3.0; c Clustered heatmap of DEGs both in GSE4745 and MitoCarta3.0; d Clustered heatmap of DEGs both in GSE5606 and MitoCarta3.0; e Clustered heatmap of DEGs both in GSE6880 and MitoCarta3.0; f PPI network of MitoDEGs; g A key cluster with 9 genes was further chosen as hub genes by MCODE; h Top 10 hub genes explored by CytoHubba