Figure 3.

TGF-β exposure impacts the transcriptome of human Vγ9Vδ2 T cells. Human PBL-expanded Vγ9Vδ2 T cells were pretreated, or not, with TGF-β (10 ng/mL) for 72 h prior to RNA extraction. Comparative DGEseq analyses were performed on bulk RNAseq samples, data were analyzed using the R software. MA plot (A) and heat maps (B) and (C) representing genes (indicated functions) that have been retrieved as differentially expressed following TGF-β exposure or not (Untreated). Colored scale, fold change expression. Down-regulated genes (blue); Up-regulated genes (red).