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. 2023 Jan 18;57(4):1731–1742. doi: 10.1021/acs.est.2c07281

Figure 1.

Figure 1

Effect of PCBs on MSC metabolic activity is highly dependent on serum concentration. The metabolic activity of MSCs was determined using XTT after 48 h of exposure to 5 or 10 μM concentrations of Aroclor 1016, Aroclor 1254, or Cabinet Mixture dissolved in (A) 15% FBS media or (B) 0.5% FBS media. Bars represent mean and error bars are SEM. Ordinary one-way ANOVA, * designates a significant difference (p < 0.05) between the indicated group and vehicle control (0 μM)-treated MSCs after Dunnett multiple comparison corrections. n = 8 biological replicates with adipose MSC donor 2334 (representative of 4 experiments).