Table 5. Strongest gene-environment interaction models, as identified by GMDR.
Model | Testing accuracy (%) | Training accuracy (%) | P-value | Cross-validation consistency |
---|---|---|---|---|
ERI | 0.583 | 0.585 | p = 0.011 | 10/10 |
ERI ×rs1360780 | 0.585 | 0.575 | p = 0.055 | 10/10 |
ERI ×rs1360780×rs3800373 | 0.589 | 0.585 | p = 0.011 | 10/10 |
Notes.
Adjusted for gender, age, ethnicity, marital status, smoking status and alcohol consumption.