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Macrophages in the tumor microenvironment. Other cells in the tumor microenvironment can affect the polarization and function of macrophages. Under the action of some cytokines, macrophages are polarized into two types, M1 and M2. M1 plays an anti-tumor role, and M2 plays a pro-tumor role. Ab, denotes antibodies; IC, denotes immune complexes; and LT, stands for leukotrienes.
