Table 1:
Age, body mass index, and general characteristics in controls and bipolar disorder cases.
| Parameters | Control (n=80) | Bipolar disorder (n=80) | P-value |
|---|---|---|---|
| Age (years) | 37.6±7.6 | 34.2±9.8 | 0.015* |
| Gender (Male/Female) | 34/46 | 31/49 | |
| Body mass index (kg/m2) | 26.46±2.8 | 24.58±3.3 | 0.029* |
| Socioeconomic status (APL/BPL) | 4/76 | 11/69 | |
| Education (graduate/non-graduate) | 14/66 | 37/43 | |
| Duration of disease (years) | ---- | 5 (1–31) | |
| Age at onset (years) | ---- | 25 (18–44) | |
| YMRS | ---- | 2.35±2.99 | |
| HDRS | ---- | 2.9±3.1 | |
| Suicidal ideation/behavior | ---- | 10 | |
| Treatment | |||
| Lithium monotherapy | |||
| Lithium combination therapy | ---- | 47 | |
| 33 | |||
| Matrix metalloproteinase-9 (µg/L) | 571.47 (54.87–2067.7) | 963.75 (179.20–7816.2) | <0.001* |
HDRS: Hamilton depression rating scale