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. 2022 Dec 16;13(4):691–695. doi: 10.25259/JNRP-2022-6-34

Table 2:

Genotyping and allele frequency data of rs17576 polymorphism between controls and bipolar disorder cases.

rs17576 Controls (n=80) (%) Bipolar disorder (n=80) (%) P-value OR (95% CI) (%)
Genotype
AA 25 (31) 16 (20)
AG 32 (40) 34 (42) 0.2893 0.6062 (0.2729–1.330)
GG 23 (29) 30 (38) 0.7126 1.228 (0.5934–2.539)
Allele
A (wild) 82 (51) 66 (41) 0.0926 0.6679 (0.4293–1.039)
G (Mutant) 78 (49) 94 (59)
Dominant model
GG+AG 55 (69) 64 (80) 0.1474 1.818 (0.8817–3.750)
AA 25 (31) 16 (20)
Recessive model
AA+AG 57 (71) 50 (62) 0.3135 0.6725 (0.3466–1.305)
GG 23 (29) 30 (38)
Co-dominant model
AG 32 (40) 34 (42) 0.8724 0.9020 (4.804–1.693)
AA+GG 48 (60) 46 (58)
Homozygote model
AA 25 (31) 16 (20) 0.1381 0.4907 (0.2139–1.125)
GG 23 (29) 30 (38)

CI: Confidence interval