Table 2:
rs17576 | Controls (n=80) (%) | Bipolar disorder (n=80) (%) | P-value | OR (95% CI) (%) |
---|---|---|---|---|
Genotype | ||||
AA | 25 (31) | 16 (20) | ||
AG | 32 (40) | 34 (42) | 0.2893 | 0.6062 (0.2729–1.330) |
GG | 23 (29) | 30 (38) | 0.7126 | 1.228 (0.5934–2.539) |
Allele | ||||
A (wild) | 82 (51) | 66 (41) | 0.0926 | 0.6679 (0.4293–1.039) |
G (Mutant) | 78 (49) | 94 (59) | ||
Dominant model | ||||
GG+AG | 55 (69) | 64 (80) | 0.1474 | 1.818 (0.8817–3.750) |
AA | 25 (31) | 16 (20) | ||
Recessive model | ||||
AA+AG | 57 (71) | 50 (62) | 0.3135 | 0.6725 (0.3466–1.305) |
GG | 23 (29) | 30 (38) | ||
Co-dominant model | ||||
AG | 32 (40) | 34 (42) | 0.8724 | 0.9020 (4.804–1.693) |
AA+GG | 48 (60) | 46 (58) | ||
Homozygote model | ||||
AA | 25 (31) | 16 (20) | 0.1381 | 0.4907 (0.2139–1.125) |
GG | 23 (29) | 30 (38) |
CI: Confidence interval