Table 2:
EQ-5D-5L utility scores in CNS tumor patients at pre-operative and progressive disease periods, when categorized by histology and disease severity.
| Characteristics | EQ-5D-5L utility scores, Mean (95% CI) | |||
|---|---|---|---|---|
| n | Pre-operative | n | Progressive disease | |
| All intracranial tumor | 123 | 0.711 (0.662–0.760) | 18 | 0.261 (0.144–0.378) |
| Intracranial tumor divided by histology | ||||
| Glioma | 37 | 0.584 (0.487–0.681) | 18 | 0.261 (0.144–0.378) |
| Glioblastoma | 22 | 0.554 (0.414–0.694) | 11 | 0.289* (0.131–0.446) |
| Other Glioma | 15 | 0.628* (0.488–0.768) | 7 | 0.217 (−0.013–0.446) |
| Meningioma | 45 | 0.753 (0.676–0.830) | 0 | NA |
| Schwannoma | 8 | 0.771 (0.490–1.000) | 0 | NA |
| Pituitary adenoma | 15 | 0.859 (0.784–0.935) | 0 | NA |
| Brain metastasis | 10 | 0.821* (0.698–0.943) | 0 | NA |
| Other brain tumor | 8 | 0.584* (0.327–0.842) | 0 | NA |
| Intracranial tumor divided by disease severity | ||||
| Benign | 83 | 0.742 (0.684–0.799) | 4 | 0.197* (−0.147–0.541) |
| Malignant | 40 | 0.647 (0.553–0.740) | 14 | 0.279 (0.137–0.420) |
| P-value† | 0.072 | 0.557 | ||
Normal distribution by Shapiro–Wilk test, †t-test with bias-corrected and accelerated non-parametric bootstrap technique compared between different malignancy status, n=Number of total patients, NA=Not available