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. 2022 Dec 16;13(4):740–749. doi: 10.25259/JNRP-2022-3-45

Table 2:

EQ-5D-5L utility scores in CNS tumor patients at pre-operative and progressive disease periods, when categorized by histology and disease severity.

Characteristics EQ-5D-5L utility scores, Mean (95% CI)
n Pre-operative n Progressive disease
All intracranial tumor 123 0.711 (0.662–0.760) 18 0.261 (0.144–0.378)
Intracranial tumor divided by histology
Glioma 37 0.584 (0.487–0.681) 18 0.261 (0.144–0.378)
Glioblastoma 22 0.554 (0.414–0.694) 11 0.289* (0.131–0.446)
Other Glioma 15 0.628* (0.488–0.768) 7 0.217 (−0.013–0.446)
Meningioma 45 0.753 (0.676–0.830) 0 NA
Schwannoma 8 0.771 (0.490–1.000) 0 NA
Pituitary adenoma 15 0.859 (0.784–0.935) 0 NA
Brain metastasis 10 0.821* (0.698–0.943) 0 NA
Other brain tumor 8 0.584* (0.327–0.842) 0 NA
Intracranial tumor divided by disease severity
Benign 83 0.742 (0.684–0.799) 4 0.197* (−0.147–0.541)
Malignant 40 0.647 (0.553–0.740) 14 0.279 (0.137–0.420)
P-value 0.072 0.557
*

Normal distribution by Shapiro–Wilk test, t-test with bias-corrected and accelerated non-parametric bootstrap technique compared between different malignancy status, n=Number of total patients, NA=Not available