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. Author manuscript; available in PMC: 2023 Oct 7.
Published in final edited form as: ACS Catal. 2022 Sep 19;12(19):12014–12026. doi: 10.1021/acscatal.2c03743

Scheme 11.

Scheme 11.

Challenges and Opportunities: (A) Understanding Significance of Different Mechanisms for Oxidative Addition, (B) Mechanistic Origin of Selectivity with Multinuclear Pd, (C) Substituent Effects on Selectivity, (D) Inverting Selectivity with “Stubborn” Substrates, (E) Minimizing Unwanted Difunctionalization.