Table 1.
Characteristic | Patients |
---|---|
Age median in years (IQR) | 40 ( 31.5-50.5) |
Male/female | 23/9 |
| |
Comorbidities | No. of patients (%) |
| |
Chronic kidney disease | 6 (18.5) |
Diabetes mellitus | 3 (9.38) |
Hypertension | 4 (12.50) |
Coronary artery disease | 3 (9.38) |
HIV | 4 (12.50) |
Chronic liver disease | 3 (9.38) |
Others | 11 (34.37) |
Status of ATT | |
ATT completed | 8 (25) |
On ATT treatment | 19 (59.37) |
ATT started after the COVID diagnosis | 5 (15.62) |
Site of TB | |
Pulmonary (previous treatment) | 7 (21.87) |
Pulmonary (current) | 8 (25) |
Tubercular meningitis | 9 (28.12) |
Abdominal TB | 3 (9.3) |
TB involving more than one site | 5 (15.62) |
Presenting complaints [n=32] | No. (%) |
Shortness of breath | 18 (56.25) |
Cough | 15 (46.88) |
Fever | 12 (37.50) |
Altered sensorium | 12 (37.50) |
Seizure | 4 (12.50) |
Others | 13 (40.63) |
Initial respiratory support | No. (%) |
Room air | 8 (25) |
Oxygen by face mask | 8 (25) |
Oxygen by HFNC | 7 (21.8) |
Invasive ventilation | 9 (28.1) |
Highest respiratory support | |
Oxygen by face mask | 8 (25) |
Oxygen by HFNC | 5 (15.6) |
Invasive ventilation | 19 (59.3) |
Chest X-ray findings | No. (%) |
Active TB | 12 (37.50) |
Post TB sequelae | 10 (31.2) |
Features of COVID | 23 (71.8) |
| |
Severity indices and inflammatory markers | Median (IQR) |
| |
Initial SOFA (n=32) | 4 (3-7) |
IL6 (pg/mL) (n=26) | 53.5 (19-105) |
Ferritin (µg/L ) (n=24) | 405 (216-940) |
CRP (mg/dL) (n=22) | 9.3 (4.05-20.7) |
Procalcitonin (ng/mL) (n=16) | 2.8 9 (0.4-6.6) |
SOFA at 48 h (n=29) | 5 (4-6) |
Duration of hospital stay (days) (n=32) | 11.5 (7-19.5) |
Data are presented as median [IQR] or number (percentages). IQR=Interquartile range, HIV=Human immunodeficiency virus, ATT=Anti tubercular treatment, TB=Tuberculosis, HFNC=High frequency nasal cannula, SOFA=Sequential Organ Failure Assessment, IL-6=Interleukin- 6, CRP=C-reactive protein