Skip to main content
. 2022 Jul 14;3(5):410–427. doi: 10.1158/2643-3230.BCD-21-0192

Figure 1.

Figure 1. Gain/amplification affecting chromosomes 9p, 19p, and 21q in AEL. A, Complex SVs affecting chromosomes 19 and 21 for a representative case (UPN091). Left, CNVs and SVs are shown along chromosome ideograms. Chromosomes 19 (Chr 19) and 21 (Chr 21) are highlighted. Chromothripsis lesions involving chromosomes 19 and 21 are shown on the right. Yellow rectangles indicate the loci of EPOR and ERG/ETS2. B, An example of CNV (UPN093). The top and bottom panels show typical CN amplifications in chromosomes 9p, 19p, and 21q identified by WGS and the ideogram of the corresponding chromosomes.

Gain/amplification affecting chromosomes 9p, 19p, and 21q in AEL. A, Complex SVs affecting chromosomes 19 and 21 for a representative case (UPN091). Left, CNVs and SVs are shown along chromosome ideograms. Chromosomes 19 (Chr 19) and 21 (Chr 21) are highlighted. Chromothripsis lesions involving chromosomes 19 and 21 are shown on the right. Yellow rectangles indicate the loci of EPOR and ERG/ETS2. B, An example of CNV (UPN093). The top and bottom panels show typical CN amplifications in chromosomes 9p, 19p, and 21q identified by WGS and the ideogram of the corresponding chromosomes.