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. Author manuscript; available in PMC: 2023 Feb 2.
Published in final edited form as: Cell Rep. 2022 Jan 11;38(2):110240. doi: 10.1016/j.celrep.2021.110240

Figure 4. Basal MECs require Zeb1 for regeneration in vivo and clonogenicity ex vivo.

Figure 4.

(A) Limiting dilution transplantation of control and Zeb1-depleted basal MECs. The pie charts show approximate take rate and percent fat pad filled by the mammary outgrowths.

(B) Transplants derived from Ade-Cre-infected (GFP+) basal MECs from 8-week-old Zeb1f/+ (control) and Zeb1f/f (KO) mice. See Figure S4B for additional replicates. Boxed area in (B) is shown at higher magnification.

(C) Transplants derived from basal MECs from 8-week-old control and Zeb1 MSKO mice. Data are representative of n = 3 pairs.

(D) Colony formation by basal MECs from 8-week-old control and Zeb1 MSKO mice. Shown is a summary from 3 independent experiments. Scale bars: 5 mm in (B) and (C). See Figure S4D for representative colony images.