. 2023 Feb 2;11(2):E162–E168. doi: 10.1055/a-2005-3679

Table 1. N staging of the 7 ^th and 8 ^th edition of the AJCC staging system.

	N1	N2	M1
AJCC 7 ^th edition	≥ 1 MLN in the regional LNs (H, CD, CBD, HA or PV LNs)	≥ 1 MLN in the regional LNs (PA, PC, SMA or CO LNs)	Distant metastasis
AJCC 8 ^th edition	1–3 MLN in the regional LNs (H, CD, CBD, HA, PPD or PV LNs)	≥ 4 MLN in the regional LNs described for N1	Distant metastasis (includes MLN distant to the HDL)

For both 7th and 8th edition of the AJCC staging system, Nx is defined as “Regional LNs cannot be assessed” and N0 as “No regional MLN”.

H, hilar; CD, cystic duct; CBD, common bile duct; HA, hepatic artery; PV, portal vein; PPD, posterior pancreato-duodenal; PA, peri-aortic; PC, peri-caval; SMA, superior mesenteric artery; CO, celiac; HDL, hepato-duodenal ligament.

Table 1. N staging of the 7 th and 8 th edition of the AJCC staging system.

Table 1. N staging of the 7 ^th and 8 ^th edition of the AJCC staging system.