表 2.
诱导前、诱导2周时和诱导4周时不同实验组的PD、GI和BOP(n=6)
PD, GI and BOP at baseline, 2 weeks, and 4 weeks of different induction methods (n=6)
| Time point | Group | Items | PD/mm, x±s | GI | BOP+/% | |||
| Medial | Distal | Palatal | Buccal | |||||
| PD, probing depth; GI, gingival index; BOP+, the percentage of bleeding on probing positive sites of the total detected sites; LPS, local injection of Porphyromonas gingivalis lipopolysaccharide; Ligation, cotton thread ligation. | ||||||||
| 2 weeks | LPS | Baseline | 0.75±0.31 | 0.42±0.15 | 0.92±0.45 | 0.50±0.18 | 0.67±0.21 | 0 |
| 2 weeks | 1.50±0.48 | 0.83±0.28 | 1.58±0.52 | 1.08±0.44 | 1.33±0.42 | 20.8 | ||
| P | 0.220 | 0.220 | 0.359 | 0.246 | 0.240 | 0.025 | ||
| Ligation | Baseline | 2.58±0.33 | 1.75±0.36 | 1.67±0.42 | 2.08±0.37 | 0.33±0.21 | 0 | |
| 2 weeks | 3.00±0.26 | 2.83±0.31 | 2.67±0.21 | 3.00±0.26 | 2.00±0.00 | 50.0 | ||
| P | 0.341 | 0.045 | 0.060 | 0.072 | 0.002 | < 0.001 | ||
| LPS+Ligation | Baseline | 2.50±0.34 | 2.25±0.40 | 1.75±0.44 | 2.17±0.30 | 0.17±0.17 | 0 | |
| 2 weeks | 2.91±0.20 | 2.75±0.25 | 2.83±0.21 | 2.92±0.27 | 2.00±0.00 | 83.3 | ||
| P | 0.318 | 0.317 | 0.052 | 0.097 | 0.002 | < 0.001 | ||
| 4 weeks | LPS | Baseline | 1.67±0.48 | 0.75±0.48 | 1.08±0.47 | 1.00±0.43 | 0.67±0.21 | 0 |
| 4 weeks | 2.17±0.38 | 1.33±0.42 | 2.00±0.48 | 1.67±0.44 | 1.83±0.17 | 58.3 | ||
| P | 0.432 | 0.382 | 0.205 | 0.304 | 0.009 | < 0.001 | ||
| Ligation | Baseline | 1.75±0.36 | 1.58±0.37 | 2.08±0.45 | 2.00±0.37 | 0.50±0.22 | 0 | |
| 4 weeks | 2.83±0.28 | 2.91±0.20 | 2.92±0.20 | 3.00±0.13 | 2.17±0.17 | 91.7 | ||
| P | 0.039 | 0.011 | 0.125 | 0.027 | 0.002 | < 0.001 | ||
| LPS+Ligation | Baseline | 2.17±0.31 | 2.00±0.45 | 1.67±0.42 | 2.17±0.40 | 0.17±0.17 | 0 | |
| 4 weeks | 2.92±0.20 | 3.08±0.27 | 3.17±0.17 | 3.17±0.28 | 2.33±0.21 | 95.8 | ||
| P | 0.068 | 0.065 | 0.008 | 0.068 | 0.002 | < 0.001 | ||