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. 2023 Jan 20;13:1063479. doi: 10.3389/fpsyt.2022.1063479

TABLE 3.

Comparison of clinical characteristics among BD of different severities.

Depressive P (hypo)manic P
Mild
(N = 17)
Moderate
(N = 35)
Severity
(N = 74)
Mild
(N = 22)
Moderate
(N = 37)
Severity
(N = 43)
Physical co-morbidities 3 6 19 0.796 5 5 20 0.170
   Inflammatory or Autoimmune diseasea 1 3 5 0.921 1 0 3 0.273
   Cyst or hyperplasiab 1 1 7 0.447 1 4 9 0.156
   Thyroid diseasesc 0 0 2 0.490 1 1 1 0.877
   Glycolipid metabolic diseasesd 1 1 3 0.870 1 0 4 0.157
   Cardiovascular diseasese 0 1 2 0.786 1 0 3 0.273
Mental comorbidities 2 9 24 0.445 6 13 15 0.884
   OCD 2 4 5 0.645 1 3 4 0.794
   Anxiety disordersf 0 2 2 0.510 1 2 3 0.914
   Eating disordersg 0 1 1 0.718 1 4 1 0.262
   Somatoform disorders 0 1 7 0.215 2 1 2 0.554
   Attempted suicideh 0 0 2 0.490 0 0 1 0.500
Duration of illness course 0.166 0.104
   ≤1 year 3 12 23 4 14 10
   >1 year and ≤ 3 years 9 16 22 11 10 13
   >3 years 5 7 27 4 13 19
Psychotic features 3 4 13 0.699 6 10 14 0.83
Family history of mental disorders 2 7 10 0.622 4 11 9 0.522

aIncluding all kinds of asymptomatic infectious diseases, allergic rhinitis, urticaria, eczema, psora, asthma, and irritable bowel syndrome.

bIncluding all the benign cyst, nodule, polyp and well-healed cancer.

cIncluding Grave’s diseases, thyroiditis, thyroid cyst, thyroid nodule, thyroid cancer., primary hypothyroidism.

dIncluding diabetes mellitus, impaired glucose tolerance, and hepatic adipose infiltration.

eIncluding hypertension, lacunar cerebral infarction, aneurism, phlebangioma, atherosclerosis, and varicosity.

fIncluding panic disorder, generalized anxiety disorder, and social phobia.

gIncluding bulimia nervosa and anorexia nervosa.

hFailed suicide attempt in the last two weeks.